Zyban Overdose

As with any medicine, it is possible to take too much Zyban. Symptoms of a Zyban overdose can include a rapid heart rate, seizures, and breathing problems. Among the factors that can influence the effects of a Zyban overdose are how much Zyban is taken and whether it is taken with other medicines. Treatment options for a Zyban overdose can include pumping the stomach, administering certain medicines, or giving supportive care.

 

Zyban Overdose: An Introduction

Zyban® (bupropion SR) is a prescription medicine used for smoking cessation (or to help people quit smoking). As with all medicines, it is possible for a person to take too much Zyban. The effects of a Zyban overdose will vary depending on a number of factors, including how much Zyban is taken and whether it is taken with any other medicines.
 

Symptoms of a Zyban Overdose

If a person overdoses on Zyban, the symptoms can vary. Following are some of the most common Zyban overdose symptoms:
 
  • Seizures
  • Hallucinations
  • Fainting
  • A rapid heart rate (tachycardia)
  • Irregular heart rhythms (arrhythmias)
  • A fever
  • Muscle tension, pain, and damage
  • Low blood pressure (hypotension)
  • Breathing problems
  • Coma
  • Loss of life.
     
About one-third of all Zyban overdoses cause seizures. Loss of life is more likely to occur if Zyban is taken in very large doses.
 

Treatment for a Zyban Overdose

The treatment for a Zyban overdose will also vary. If the overdose was recent, the healthcare provider may give certain medicines or place a tube into the stomach to "pump the stomach." Treatment may also involve supportive care. This type of care consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options for a Zyban overdose may include:
 
  • Fluids through an intravenous line (IV)
  • Medicines to control an irregular heart rhythm or control seizures
  • Closely monitoring the heart and lungs
  • A breathing tube to help with breathing
  • Other treatments based on complications that occur.
     
It is important that you seek medical attention immediately if you believe that you may have overdosed on Zyban.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;