Zyban Drug Interactions (Cont.)

 
Beta Blockers
Zyban may raise the levels of beta blockers in your blood, potentially increasing your risk of side effects. Depending on your particular situation, if you are taking these drugs together, your healthcare provider may need to monitor you more closely and may need to decrease your beta blocker dose.
 
Certain Arrhythmia Medications
Zyban can increase the levels of certain arrhythmia medications in your blood, possibly increasing your risk of side effects. To prevent this, your healthcare provider may need to monitor you more closely, especially when you are starting or stopping Zyban.
 
Cyclophosphamide
While it is thought that cyclophosphamide may interact with Zyban, there have been no reports of such an interaction in actual patients. Depending on your situation, if you are taking cyclophosphamide along with Zyban, your healthcare provider may choose to monitor you more closely and may adjust your doses of these medications.
 
Doxorubicin
Doxorubicin may raise the level of Zyban in your blood, which may increase your chances of side effects. Your healthcare provider may need to decrease your Zyban dose while you are taking doxorubicin.
 
Efavirenz
While it is thought that efavirenz may interact with Zyban, there have been no reports of such an interaction in actual patients. Depending on your situation, if you are taking efavirenz along with Zyban, your healthcare provider may monitor you more closely and may need to adjust your doses of these medications.
 
Levodopa
Combining Zyban and levodopa may increase your risk of side effects. To prevent this, your healthcare provider may decide to start you at a lower Zyban dosage if you are taking levodopa.
(Zyban Drug Interactions Continued: Page 4)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;