Zyban and Pregnancy

In previous animal studies involving Zyban and pregnancy, the active ingredient of Zyban (bupropion) appeared to cause an increased risk of birth defects and lower fetal weights. Preliminary studies in humans suggest that the medicine may not cause any problems during pregnancy. If you are taking Zyban and pregnancy occurs -- or if you are thinking of becoming pregnant while taking the medicine -- you should let your healthcare provider know.

Zyban and Pregnancy: An Overview

Zyban® (bupropion SR) is a pregnancy Category C medicine, meaning that it could potentially cause harm to your unborn child.
 

Zyban and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that show side effects to the fetus in animal studies but for which no adequate human studies in pregnant women have been done. A pregnancy Category C medicine may still be given to a pregnant woman if her healthcare provider believes that the benefits to the mother outweigh the possible risks to the unborn child.
 
In animal studies in which bupropion (the active ingredient of Zyban) was given to pregnant rabbits, there was an increased risk of birth defects and lower fetal weights. In humans, however, preliminary studies suggest that bupropion may not cause any problems during pregnancy.
 
It is important to note that it is not healthy for the baby if the mother smokes. Therefore, Zyban may also be given to a pregnant woman if the healthcare provider believes that the benefits of stopping smoking outweigh any possible risks to the unborn child.
 

Zyban and Pregnancy: A Summary

If you are taking Zyban and pregnancy occurs, or if you are thinking of becoming pregnant while taking the drug, let your healthcare provider know. He or she will consider the benefits and risks of taking Zyban during pregnancy before making a recommendation for your particular situation.
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Zyban to Quit Smoking

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