Zileuton is a medication that, when taken four times a day, can help prevent asthma attacks. The drug has been shown to improve breathing and reduce symptoms in both adults and children by blocking leukotriene receptors. It comes in tablet form and is available by prescription. Side effects can include nausea, headache, pain, and indigestion or heartburn.

In February 2008, the manufacturer of Zyflo announced that it has discontinued making this product. The manufacturer stated that since the longer-acting version, Zyflo CR, became available in 2007, use of immediate-release Zyflo declined significantly. Zyflo CR will still be available.

What Is Zileuton?

Zileuton (Zyflo®) is a prescription medication used to prevent asthma attacks in adults and children as young as 12 years old.
(Click What Is Zileuton Used For? for more information, including possible off-label uses of the medication.)

Potential Side Effects

As with any medicine, side effects are possible with zileuton. However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
Common side effects of zileuton include but are not limited to:
(Click Side Effects of Zileuton to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
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Zileuton (Zyflo)

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