Tracleer Uses

How Does Tracleer Work?

Tracleer is an endothelin receptor antagonist. Endothelins are proteins that have a variety of effects in the body, including on the heart, blood vessels, lungs, and kidneys. One of the things endothelins do is cause blood vessels to constrict (narrow).
 
People with PAH have higher-than-normal levels of endothelins in the body. Endothelin can bind to two receptors. Tracleer works by blocking both of those receptors, preventing endothelin from binding to them. This helps block the effects of the extra endothelin in people with PAH.
 

Is It Safe for Children to Use It?

Tracleer is not approved for use in children (usually defined as individuals younger than 18 years of age), as it has not been adequately studied in this age group. Talk to your child's healthcare provider about the risks and benefits of using this medicine in a child.
 

Can Older Adults Use Tracleer?

There were not enough individuals over the age of 65 in clinical trials to determine if older individuals would respond to the medicine any differently than younger age groups. Because older adults are more likely to have other health conditions and to take additional medications, Tracleer may need to be used cautiously in older individuals. 
 

Off-Label Tracleer Uses

On occasion, your healthcare provider may recommend this medicine for something other than the condition discussed in this article. This would be known as an "off-label" use. Some of the possible off-label uses for Tracleer may include:
 
 

Tracleer Medication Information

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