Tracleer is a prescription drug that is taken to treat pulmonary arterial hypertension (PAH). It comes in the form of a tablet that is taken twice daily, once in the morning and again in the evening. The Tracleer dosage you receive will be calculated based on your weight, other medications you are taking, and how you tolerate the drug, among other factors.
An Introduction to Dosing With Tracleer
The dose of Tracleer® (bosentan) your healthcare provider recommends will vary, depending on a number of factors, including:
- Your weight
- Other medications you are taking
- Whether you develop certain side effects.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
What Is the Recommended Tracleer Dosage?
The initial recommended Tracleer dosage for treating pulmonary arterial hypertension is usually 62.5 mg twice a day for four weeks. After four weeks, the dosage is normally increased to the recommended maintenance dose of 125 mg twice a day. However, it is recommended that people who weigh less than 40 kg (about 88 lbs) continue taking Tracleer 62.5 mg twice a day as their maintenance dose.
For people who are taking a medication called ritonavir (Norvir®), the recommended initial dose of Tracleer is usually 62.5 mg once a day or 62.5 mg every other day. The actual amount used will be based on how well Tracleer is tolerated.
Because Tracleer can cause liver damage, your healthcare provider will order regular blood tests to check your liver function. If the blood tests show early signs of liver damage, your healthcare provider may reduce your Tracleer dosage, recommend a break in treatment, or permanently stop treatment. In clinical studies, doses above 125 mg twice a day did not increase the effectiveness of the medicine, but did increase the risk for liver damage.
If you will no longer need to take Tracleer, your healthcare provider may recommend you gradually stop taking it. Stopping the medicine suddenly may cause your symptoms to become worse. Do not suddenly stop taking it unless your healthcare provider tells you to do so.