Tobramycin Inhalation Powder
You should talk with your healthcare provider prior to using this medication if you have:
- Kidney disease, such as kidney failure (renal failure)
- Hearing problems
- A balance disorder or dizziness
- A disorder that affects your muscles, such as myasthenia gravis or Parkinson's disease
- Had an organ transplant
- Breathing problems, such as wheezing, coughing, or chest tightness
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Tobi Podhaler and Pregnancy)
- Breastfeeding (see Tobi Podhaler and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Tobramycin Inhalation Powder to learn more, including information on who should not use the drug.)
As the name implies, tobramycin inhalation powder contains the antibiotic tobramycin. The drug works by killing bacteria. It does this by interfering with bacteria's ability to make proteins, which are necessary for the bacteria to grow and multiply.
Tobramycin inhalation powder has been studied in clinical trials that included people with cystic fibrosis who had the bacteria P. aeruginosa in their lungs. In one study, tobramycin inhalation powder improved lung function more so than the placebo (an inhaled "medicine" with no active ingredients).
The drug also reduced the need for hospitalization and additional antibiotics. More specifically, 4.4 percent of people given tobramycin inhalation powder needed to be hospitalized, and 8.7 percent required additional antibiotics for their infection. In comparison, of those given the placebo, 12.2 percent needed to be hospitalized and 10.2 percent needed additional antibiotics.