Drug Interactions With Tobramycin Inhalation Powder

More Detail on Drug Interactions With Tobramycin Inhalation Powder

The following sections explain in detail the potentially negative interactions that can occur when tobramycin inhalation powder is combined with any of the drugs listed above.
 
Amphotericin B
Using tobramycin inhalation powder with amphotericin B could increase your risk for kidney problems. Your healthcare provider may choose to monitor your kidney function more closely using blood and urine tests if you take these medicines together.  
 
Bisphosphonates
Combining tobramycin inhalation powder with a bisphosphonate could lead to low blood calcium levels (hypocalcemia). Your healthcare provider may choose to monitor your blood calcium levels if you take these drugs together.
 
Carboplatin
Taking tobramycin inhalation powder with carboplatin could increase your risk for inner ear damage, which could lead to hearing loss, ringing in the ears, or balance problems. Talk to your healthcare provider before taking these medicines together.
 
Cephalosporin Antibiotics
Combining tobramycin inhalation powder with a cephalosporin antibiotic could increase the risk for kidney problems. Your healthcare provider may choose to monitor your kidney function more closely using blood and urine tests if you take these medicines together.  
 
Cisplatin
Combining tobramycin inhalation powder with cisplatin could increase the risk for kidney problems. Your healthcare provider may choose to monitor your kidney function more closely using blood and urine tests if you take these drugs together.  
 
Colistimethate
Combining tobramycin inhalation powder with a colistimethate could increase your risk for certain side effects, including kidney problems. Your healthcare provider may choose to monitor you more closely if you take these medicines together.  
 
Cyclosporine
Combining tobramycin inhalation powder with cyclosporine could increase your risk for kidney problems. Your healthcare provider may choose to monitor your kidney function more closely using blood and urine tests if you take these drugs together.  
 
Gallium Nitrate
Combining tobramycin inhalation powder with gallium nitrate could increase the risk for kidney problems. It is recommended that these medicines not be used together if at all possible. If you need to take them both, your healthcare provider will closely monitor your kidney function using blood and urine tests.
 
Loop Diuretics
Taking loop diuretics with tobramycin inhalation powder could increase the chance that you will experience tobramycin inhalation powder side effects, including kidney and ear problems. Talk to your healthcare provider before taking these drugs together. He or she may want to monitor you more closely for potential problems.
 
Mannitol
According to the manufacturer of tobramycin inhalation powder, this medicine should not be used in combination with mannitol, as doing so could increase the risk for tobramycin inhalation powder side effects.
 
Neuromuscular-Blocking Medications
Combining tobramycin inhalation powder with neuromuscular-blocking medicines could increase your risk for certain serious side effects, including abnormally slow and shallow breathing. Your healthcare provider will monitor you more closely if you take these drugs together.
 
NSAIDs
Combining tobramycin inhalation powder with an NSAID may increase the risk for kidney problems. This interaction appears to mainly be a concern in premature infants. However, your healthcare provider may choose to monitor your kidney function more closely using blood and urine tests if you take such drugs together, just to be safe.  
 
Other Aminoglycoside Antibiotics
If you take tobramycin inhalation powder with other aminoglycoside antibiotics, you may have a higher risk for side effects and may need to be monitored more closely.
 
Vancomycin
Combining tobramycin inhalation powder with vancomycin could increase the risk for kidney problems. Your healthcare provider may choose to monitor your kidney function more closely using blood and urine tests if you take these medicines together.  
 

Tobramycin Inhalation Powder Information

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