Side Effects of Tiotropium

In clinical studies, common side effects of tiotropium included upper respiratory infections, dry mouth, and sore throat. These side effects are typically minor -- if they even occur -- and are easily treated. However, if you develop wheezing, chest pain, severe constipation, or other serious side effects, contact your healthcare provider right away.

Tiotropium Bromide Inhalation Powder

Side Effects of Tiotropium: An Introduction

As with any medicine, side effects are possible with tiotropium bromide (Spiriva^®); however, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.

(This article covers many, but not all, of the possible side effects with tiotropium. Your healthcare provider can discuss a more complete list of tiotropium side effects with you.)

Common Side Effects of Tiotropium

Tiotropium has been studied thoroughly in clinical trials, in which a group of people taking the drug have side effects documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.

In these studies, the most common side effects of tiotropium included:

Upper respiratory infection (such as the common cold) -- in up to 41 percent of people
Dry mouth -- up to 16 percent (see Spiriva and Dry Mouth)
Sinus infection -- up to 11 percent
Sore throat -- up to 9 percent
Bladder infection (urinary tract infection or UTI) -- up to 7 percent.

Other common tiotropium side effects (occurring in 1 to 6 percent of people) included:

Abdominal pain (stomach pain)
Constipation
Indigestion or heartburn
Vomiting
Muscle pain
Yeast infection
Nosebleeds
Stuffy or runny nose.

(Side Effects of Tiotropium Continued: Page 2)