Sirturo Side Effects
Even though most people tolerate Sirturo well, side effects are possible and may include nausea, headaches, and a loss of appetite. Most of these reactions are minor and easy to treat. However, contact your healthcare provider if you develop problems that may be more serious, such as an irregular heartbeat, fainting, or yellowing of the whites of the eyes or skin.
Just like any medicine, Sirturo™ (bedaquiline) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Sirturo. Your healthcare provider can discuss a more complete list with you.)
Sirturo has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and compared to those that occurred in a similar group of people taking a placebo (a "sugar pill" with no active ingredients). Therefore, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common Sirturo side effects included:
- Nausea -- in up to 38 percent of people
- Joint pain -- up to 32.9 percent
- Headache -- up to 27.8 percent
- Coughing up blood -- up to 17.7 percent
- Chest pain -- up to 11.4 percent
- Increase in liver enzymes, which may be a sign of liver damage -- up to 8.9 percent
- Loss of appetite -- up to 8.9 percent
- Rash -- up to 7.6 percent
- Increase in an enzyme that may indicate damage to the pancreas -- up to 2.5 percent.