Roflumilast

What If I Overdose on This Medication?

It is unknown what exactly to expect from an overdose with this medication. If you happen to take too much roflumilast, seek immediate medical attention.
 
(Click Daliresp Overdose for more information.)
 

What Should I Do If I Forget a Dose?

If you forget to take a dose of roflumilast, take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and continue with your regular schedule. Do not take a double dose.
 

How Does It Work?

Roflumilast inhibits an enzyme called phosphodiesterase type-4 (PDE4). By inhibiting PDE4, roflumilast increases the level of cyclic adenosine monophosphate (cAMP) in cells. It is not entirely clear how this action helps with COPD treatment, although it is thought that anti-inflammatory actions may be involved.
 

Clinical Effects

Clinical studies have shown that roflumilast reduces the risk of moderate or severe COPD exacerbations by 15 to 18 percent, compared to treatment with a placebo (a "sugar pill" that does not contain any active ingredients).
 

When and How to Take This Medication

Some general considerations to keep in mind during treatment include the following:
 
  • Roflumilast comes in tablet form. It is usually taken by mouth once a day.
  • Try to take your dose at the same time each day to keep an even level in your blood.
  • You can take this medication with or without food.
  • For this medication to work properly, it must be taken as prescribed.
 

Storage Information

Roflumilast should be stored at room temperature, away from moisture. Keep this and all other medications out of the reach of children.
 

Roflumilast Drug Information

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