Drug Interactions With Roflumilast

Drug Interactions With Roflumilast Explained

The following sections explain in detail the potentially negative interactions that can occur when roflumilast is combined with any of the drugs listed above.
 
CYP 1A2 Inhibitors
The body breaks down roflumilast using enzymes in the liver known as CYP 1A2 enzymes. Some other medications (known as CYP 1A2 inhibitors) can decrease the activity of these enzymes. Combining roflumilast with one of these CYP 1A2 inhibitors may increase the level of roflumilast in your body, increasing your risk for serious side effects. Check with your healthcare provider before taking such medications together.
 
CYP 3A4 Inducers
The body breaks down roflumilast using enzymes in the liver known as CYP 3A4 enzymes. Some other medications (known as CYP 3A4 inducers) can increase the activity of these enzymes. Combining roflumilast with one of these CYP 3A4 inducers may decrease the level of roflumilast in your body, making it less effective. Check with your healthcare provider before taking such medications together.
 
CYP 3A4 Inhibitors
The body breaks down roflumilast using enzymes in the liver known as CYP 3A4 enzymes. Some other medications (known as CYP 3A4 inhibitors) can decrease the activity of these enzymes. Combining roflumilast with one of these CYP 3A4 inhibitors may increase the level of roflumilast in your body, increasing your risk for serious side effects. Check with your healthcare provider before taking such medications together.
 

Final Thoughts

It is possible that not all roflumilast drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.

Roflumilast Drug Information

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