Revatio Warnings and Precautions
Specific Precautions and Warnings for RevatioSome warnings and precautions to be aware of prior to taking this drug include the following:
- There have been cases of serious side effects, such as heart attack, stroke, bleeding in the brain or lungs, and sudden death in people taking sildenafil citrate for erectile dysfunction. Sildenafil citrate is the main active ingredient in Revatio. If you have a heart or blood vessel disease (cardiovascular disease) or significant heart disease risk factors, you may have an increased risk of these serious side effects.
- Revatio is not approved for use in children. Studies suggest that using Revatio to treat pulmonary arterial hypertension increases the risk of death in children.
- Revatio can cause low blood pressure (hypotension). If your blood pressure becomes too low, you may become dizzy or faint. If you do feel dizzy or faint while taking Revatio, lie down. You can reduce the risk of falling down from dizziness by sitting and standing up slowly. Also, make sure you have something stable to hold on to when changing to a seated or standing position.
- PDE5 inhibitors such as Revatio have been associated with rare cases of a condition called nonarteritic anterior ischemic optic neuropathy (NAION). This condition can lead to sudden decrease or loss of vision in one or both eyes. The vision loss can be permanent. If you experience any problems with your vision while taking Revatio, contact your healthcare provider immediately.
- A sudden decrease or loss of hearing has occurred in people taking Revatio and other PDE5 inhibitors. Dizziness and ringing in the ears sometimes occurred with the hearing loss. If you notice a change in your hearing or experience dizziness and ringing in your ears while taking Revatio, contact your healthcare provider immediately.
- Phosphodiesterase type-5 (PDE5) inhibitors, such as Revatio, have been associated with a rare but serious condition called priapism. Priapism is a persistent and usually painful erection that lasts for more than four hours. If you experience an erection for longer than four hours while taking Revatio, seek immediate medical attention. If not treated immediately, priapism can cause impotence and permanent damage to the penis.
- The generic name for Revatio is sildenafil citrate. Sildenafil citrate is also marketed as Viagra®, which is used to treat erectile dysfunction. Do not take Revatio with Viagra or other PDE5 inhibitors, such as Cialis® (tadalafil) and Levitra® (vardenafil).
- Revatio can interact with a number of other medications (see Revatio Drug Interactions).
- Revatio is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are currently unknown (see Revatio and Pregnancy).
- It is unknown if Revatio passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Revatio and Breastfeeding).