There are two types of medications that can be used for pulmonary embolism treatment.
They are:
- Anticoagulants
- Thrombin inhibitors.
Anticoagulants
Anticoagulants, also known as blood thinners, decrease the blood's ability to clot. Anticoagulants are used to stop clots from getting bigger and to prevent blood clots from forming. However, anticoagulants do not break up blood clots that have already formed. Anticoagulants can be taken:
- As a pill (warfarin)
- As an injection or shot (heparin)
- Intravenously, or through an IV (heparin).
Heparin and warfarin (Coumadin®, Jantoven®) may be given at the same time. Heparin will act quickly, while warfarin will take two to three days before it will start to work. Once the warfarin is working, the heparin will be stopped.
However, pregnant women cannot take warfarin, so they will be treated only with heparin.
Treatment with anticoagulants usually lasts for three to six months. However, the following situations may change the length of treatment:
- If a blood clot occurred after a short-term risk like surgery, treatment may be shorter.
- If you have had clots before, longer treatment will be needed.
- If you have another illness (like cancer) that you are being treated for, treatment will be needed as long as those risk factors are present.
The most common side effect of anticoagulants is bleeding. You should call your doctor immediately if you are taking warfarin or heparin and have easy bruising or bleeding. Warfarin also interacts with many other medications. Therefore, you should tell your doctor all of the medications you are on, including over-the-counter medications.
Thrombin inhibitors
Thrombin inhibitors are new medications that interfere with the clotting process. Thrombin inhibitors are used to treat some types of clots and for patients who cannot take heparin.