What Is Omalizumab Used For?

Using Omalizumab for Chronic Idiopathic Urticaria

Omalizumab is also approved for chronic idiopathic urticaria (which means chronic hives of unknown cause). Hives are red, raised welts on the skin. They are usually very itchy. Hives are commonly caused by allergies, although other factors (such as stress) can also cause them.
 
Many people get hives chronically without finding any cause. Omalizumab is approved to treat chronic hives of unknown cause in people age 12 and over who still have symptoms despite treatment with antihistamine medications.
 

How Does Omalizumab Work?

Omalizumab is an asthma medication that belongs to a group of drugs called monoclonal antibodies. Monoclonal antibodies are used to treat a wide variety of conditions, including asthma. Omalizumab works by binding to IgE antibodies. IgE antibodies play an important role in allergic reactions. By binding to IgE antibodies, omalizumab blocks their effects. By preventing allergic reactions, omalizumab can help to prevent asthma attacks.
 
It is currently unknown how exactly omalizumab works to treat chronic idiopathic urticaria.
 

Omalizumab Use in Children

Omalizumab is approved for the treatment of asthma and chronic idiopathic uricaria in children 12 years of age and older. Be sure to talk with your healthcare provider about the the potential risks and benefits of using this medication in children.
 

Off-Label Omalizumab Uses

On occasion, your healthcare provider may recommend omalizumab for something other than preventing asthma attacks. At this time, off-label omalizumab uses can include:
 
  • Preventing severe food allergies
  • Preventing other types of allergies, such as seasonal allergies.
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