Omalizumab Dosing

The omalizumab dosing guidelines your healthcare provider follows will vary depending on factors such as your weight and the results of a lab test to measure the levels of a certain antibody. If these test results show a low level of the antibody, you can take omalizumab every four weeks. However, if your antibody levels are higher, you may have to take omalizumab every two weeks. Your healthcare provider is usually the one who will administer the omalizumab injections.

An Introduction to Omalizumab Dosing

The dose of omalizumab (Xolair®) that your healthcare provider recommends will vary depending on a number of factors, including:
  • Your weight
  • The medical condition being treated
  • The results of a lab test measuring your IgE level. IgE is an antibody that plays an important role in allergic reactions.
As always, do not adjust your omalizumab dose unless your healthcare provider specifically instructs you to do so.

Dose of Omalizumab for Asthma

When treating asthma, omalizumab is given by injection every two to four weeks. In general, smaller people or people with lower IgE levels can take omalizumab every four weeks, and those who are larger or who have higher IgE levels will need omalizumab every two weeks.

The exact dose depends on your weight and your IgE level. Your IgE level will be measured using a blood test before you start omalizumab. If you have your IgE level measured again while you are taking omalizumab, your dose should not be adjusted based on this measurement (since omalizumab affects IgE levels).

Omalizumab Dosing for Chronic Idiopathic Urticaria

When treating chronic idiopathic urticaria, the standard dosage of omalizumab is 150 mg or 300 mg given by injection once every four weeks. When used for this condition, the amount does not vary by weight or IgE levels.
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Omalizumab for Asthma

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