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Now that the patent for brand-name Zyban has expired, generic Zyban is available. The medication is sold under the names buproprion SR and Buproban, and is available in one 150-mg strength. Generic Zyban has been given an AB rating by the FDA, which means that it is considered equivalent to the brand-name medicine. However, it may have different fillers, dyes, or other inactive ingredients -- which could cause problems for people with certain allergies or sensitivities.

An Introduction to Generic Zyban

Zyban® (bupropion SR) is a prescription medicine used to help people stop smoking (also known as smoking cessation).
It was first manufactured by GlaxoSmithKline. However, the patent has since expired, and generic Zyban is now available.

Names and Strengths of Generic Zyban

Generic manufacturers may choose to use a standard generic name or to create their own name. Because of this, generic Zyban tablets are sold under two names: bupropion SR and Buproban®. Generic Zyban tablets are available in one strength: Bupropion SR 150 mg tablets (or Buproban 150 mg tablets).

Who Makes Generic Zyban?

Generic Zyban is made by two companies. Buproban is made by Teva Pharmaceuticals. Bupropion SR is made by Sandoz Pharmaceuticals.

Are Generic Versions as Good as Brand-Name Zyban?

All generic medications must have certain tests to compare them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generic versions are equivalent to the brand-name medications and assigns a rating to each one. An "AB" rating means that the FDA has determined that a generic medication is equivalent to a brand-name medication. All of the generic Zyban versions currently available have an "AB" rating, meaning that they should be equivalent to brand-name Zyban. However, generic Wellbutrin SR® (which is also sold under the name Bupropion SR) is technically not equivalent to Zyban, due to differences in the prescribing information -- though healthcare professionals usually use them interchangeably.
Keep in mind that generic medications are allowed to have different inactive ingredients from the brand-name versions. These inactive ingredients -- which might include fillers, dyes, or other ingredients -- could cause problems for people with certain allergies or sensitivities.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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