Zileuton is a medication that, when taken four times a day, can help prevent asthma attacks. The drug has been shown to improve breathing and reduce symptoms in both adults and children by blocking leukotriene receptors. It comes in tablet form and is available by prescription. Side effects can include nausea, headache, pain, and indigestion or heartburn.
In February 2008, the manufacturer of Zyflo announced that it has discontinued making this product. The manufacturer stated that since the longer-acting version, Zyflo CR, became available in 2007, use of immediate-release Zyflo declined significantly. Zyflo CR will still be available.
What Is Zileuton?
Zileuton (Zyflo®) is a prescription medication used to prevent asthma attacks in adults and children as young as 12 years old.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed April 26, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
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