Healthcare providers may prescribe Tobi® (tobramycin inhalation solution) to treat a certain bacterial infection in people who have cystic fibrosis. Specifically, this prescription antibiotic is approved to treat infections caused by the bacterium Pseudomonas aeruginosa. This medicine is approved for use in adults and children as young as six years old.
Tobi inhalation solution is designed to be used with a nebulizer and an air compressor. The medicine forms a mist that is inhaled. There is only one standard dose of this medication -- one ampule (300 mg per 5 mL) of solution inhaled twice daily, with about 12 hours between doses. This dosing schedule is continued for 28 days, followed by a 28-day break from using the medicine before resuming treatment.
Although most people who use this medicine tolerate it fairly well, side effects are possible. Some of the potential side effects include a sore throat, runny nose, and a worsening cough. Fortunately, most reactions to the drug tend to be mild and easy to treat.
(Click Tobi for more information on this nebulizer solution, including how it works, dosing instructions, and general safety precautions.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Tobi [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2009 November.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed June 13, 2013.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed June 13, 2013.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed June 13, 2013.
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