Tobi® (tobramycin inhalation solution) is an antibiotic prescribed to treat an infection caused by Pseudomonas aeruginosa bacteria in people who have cystic fibrosis. This medication comes as a liquid that is turned into a mist, using an air compressor and nebulizer. Before using Tobi, review the drug's safety information with your healthcare provider, especially if you have hearing problems, kidney disease, or a disorder that affects your muscles. Also, make sure your healthcare provider is aware of all medications, supplements, and vitamins you are taking.
Dosing for Tobi is standard for everyone -- one ampule (300 mg per 5 mL inhaled solution) inhaled twice daily, with about 12 hours between doses. You will use Tobi for 28 days, followed by a 28-day break before you start your next 28-day treatment cycle.
(Click Tobi for more information, including how it works, possible side effects, and generic availability.)
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: ArthurSchoenstadt, MD
List of references (click here):
Tobi [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2009 November.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed June 13, 2013.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed June 13, 2013.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed June 13, 2013.
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