Lungs Home > Accolate Side Effects

Headaches, nausea, and infections are some of the most common side effects reported with Accolate. Reactions to this medication are mostly minor and either don't require treatment or are easily treated. However, there are some problems that you should report to your healthcare provider immediately, including signs of an allergic reaction, any signs of liver damage, or worsening of asthma.

An Introduction to Accolate Side Effects

As with any medicine, side effects are possible with Accolate® (zafirlukast); however, not everyone who takes the medication will experience problems. In fact, most people tolerate it well. If side effects do occur, in most cases they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Accolate. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Accolate

Accolate has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and are then compared to those that occur in another group of people not taking the medicine. In these studies, the most common Accolate side effects included:
  • Headaches -- in up to 12.9 percent of people
  • Infections -- up to 3.5 percent
  • Nausea -- up to 3.1 percent
  • Diarrhea -- up to 2.8 percent.
Some other common reactions (occurring in 1 percent to 2 percent of people) included:
  • General pain
  • Weakness
  • Abdominal pain (stomach pain)
  • Accidental injury
  • Dizziness
  • Muscle pain
  • Fever
  • Back pain
  • Vomiting
  • Indigestion or heartburn.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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