Dornase Alfa -- Cystic Fibrosis Medication
If you have been diagnosed with cystic fibrosis (CF), your healthcare provider may recommend a medication called dornase alfa (Pulmozyme®). This prescription drug breaks down the extra DNA that often causes sputum to become thick, which results in better lung function. Although most people tolerate it well, side effects are possible and may include sore throat, voice changes, and chest pain.
Many factors will play a role in the dosage your healthcare provider prescribes, including how you initially respond to the drug and if other medical conditions are present. In most cases, a single dose of 2.5 mg is taken once daily. However, some people may need to take dornase alfa twice a day.
(For more details on this cystic fibrosis medication, including other potential side effects and information on how it performed in clinical trials, click Dornase Alfa.)