What Is Linezolid Used For?

How Does This Medication Work?

Linezolid belongs to the oxazolidinone class of antibiotics. It works by attaching to bacterial ribosomes (ribosomes are parts of cells that make protein).
Specifically, linezolid binds to the 50S subunit of the bacterial ribosome and prevents it from going on to make proteins, which are necessary for the bacteria to grow and multiply. By preventing bacteria from making proteins, linezolid stops bacterial growth (this is known as being bacteriostatic) and kills bacteria (this is known as being bactericidal).
Because human ribosomes do not have 50S subunits, linezolid does not interfere with protein production in humans.

Can Children Use It?

Linezolid is approved for the treatment of infections in children of all ages, including newborns.

Is Linezolid Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this product for something other than the conditions discussed in this article. Using linezolid for an infection not discussed in this article is considered an "off-label" use. For example, some of these off-label linezolid uses include the treatment of:
  • Catheter-related bloodstream infections
  • Febrile neutropenia in people with cancer
  • Bone infections (osteomyelitis)
  • Mycobacteriosis (infections caused by bacteria called mycobacteria).

Linezolid Drug Information

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