Precautions and Warnings With Linezolid

If you have kidney disease, phenylketonuria, or any allergies, tell your healthcare provider before taking linezolid. This antibiotic is not suitable for everyone, and there are a number of safety issues to be aware of before starting treatment. Warnings and precautions also apply to people who are allergic to any of the ingredients used to make linezolid, who should avoid the drug.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking linezolid (Zyvox®) if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • High blood pressure (hypertension) or a history of high blood pressure
  • Bone marrow problems, such as leukemia, anemia, lymphoma, or recent chemotherapy
  • Pheochromocytoma, a rare tumor of the adrenal gland
  • Carcinoid syndrome (symptoms caused by carcinoid tumors, which are most often found in the gastrointestinal tract or the lungs)
  • Untreated hyperthyroidism (overactive thyroid), inflammation of the thyroid gland, or high thyroid hormone levels in your blood
  • Ever had a seizure
  • Phenylketonuria (a problem with amino acids)
  • Recently been treated with other antibiotics or are currently being treated for another infection with other antibiotics
  • Any allergies, including to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medications, vitamins, and herbal supplements.
 

Linezolid Drug Information

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