Drug Interactions With Linezolid

Methyldopa
Taking methyldopa and linezolid together may increase your risk of dangerous side effects, such as high blood pressure (hypertension). If you take these medications together, your healthcare provider will need to monitor you closely.
 
Narcotic Pain Medications
Taking linezolid with narcotics can increase your chance of serious side effects, including low blood pressure (hypotension) or serotonin syndrome, a potentially life-threatening reaction. Talk to your healthcare provider before taking these medications together.
 
Pressors
Combining pressors and linezolid may increase your risk of dangerous side effects, such as high blood pressure (hypertension). These medications should be used together with caution. If you must take both of these drugs, your healthcare provider will need to monitor you closely.
 
Tramadol
Combining linezolid with tramadol increases your risk of a dangerous and potentially life-threatening reaction called serotonin syndrome. If you take these medications together, your healthcare provider should monitor you closely for signs of this reaction (see Precautions and Warnings With Linezolid).
 
Triptans
Taking linezolid with a triptan medication may increase your risk of a dangerous and potentially life-threatening reaction called serotonin syndrome. If you take these medications together, your healthcare provider should monitor you closely for signs of this reaction (see Precautions and Warnings With Linezolid for more information).
 
Tryptophan
Taking tryptophan and linezolid together increases the risk of dangerous side effects, such as high blood pressure (hypertension), confusion, or agitation. Talk to your healthcare provider before combining these drugs.
 

Linezolid Drug Information

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