Side Effects of Ipratropium and Albuterol Inhaler

Commonly reported side effects of ipratropium and albuterol inhalers include difficulty breathing, headaches, and coughing. Less common side effects include nausea, a sore throat, and sinus infections. There are also a number of ipratropium and albuterol inhaler side effects that are more serious and that should be reported to a healthcare provider right away, such as a rapid heart rate, high blood pressure, and vision changes.

Side Effects of Ipratropium and Albuterol Inhaler: An Introduction

In order to comply with the Montreal Protocol on Substances That Deplete the Ozone Layer, Combivent inhalers (in their original form) will not be available after July 2013 because they contain chlorofluorocarbons (CFCs), chemicals that deplete the ozone layer. A new formulation, Combivent Respimat, became available starting in October 2012. People using the old Combivent inhaler will need to get a new prescription in order to switch to the new Combivent Respimat inhaler.


As with any medicine, side effects are possible with the ipratropium and albuterol inhaler (Combivent®). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with the ipratropium and albuterol inhaler. Your healthcare provider can discuss a more complete list of the ipratropium and albuterol inhaler side effects with you.)

Side Effects of Ipratropium and Albuterol Inhaler to Report

Some side effects with the ipratropium and albuterol inhaler, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but not limited to:
  • Worsening breathing problems
  • Severe constipation
  • Difficulty passing urine
  • An irregular heart rhythm (arrhythmia) or a rapid heart rate (tachycardia)
  • Low blood pressure (hypotension)
  • Vision changes
  • High blood pressure (hypertension)
  • Anxiety
  • Worsening of diabetes
  • Chest pain
  • Signs of an allergic reaction, such as unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing.

Information on Ipratropium and Albuterol

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