Drug Interactions With Dornase Alfa

Dornase alfa (Pulmozyme®) is not known to interact with any other medications. During clinical studies, dornase alfa has been used together successfully with other cystic fibrosis medications, such as:
 
  • Antibiotics, including oral, inhaled, and IV antibiotics
  • Enzyme supplements
  • Vitamins
  • Steroids, including oral and inhaled steroids
  • Pain medications
  • Bronchodilators (medications to open the airways).
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Because no studies have been done specifically to look for drug interactions with dornase alfa, it is possible that there are interactions that are not known at this time. Therefore, you should talk with your pharmacist or healthcare provider about drug interactions that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;