Drug Interactions With Dextromethorphan Polistirex

Drug Interactions With Dextromethorphan Polistirex Explained

The following sections explain in detail the potentially negative interactions that can occur when dextromethorphan polistirex is combined with any of the drugs listed above.
 
Alcohol
Do not drink alcohol while taking dextromethorphan polistirex. Alcohol will increase the effects of this medication on the brain, potentially increasing the risk of dangerous problems, such as a coma or slow or irregular breathing. In addition, alcohol consumption can make the effects of a dextromethorphan polistirex overdose more serious.
 
Amphetamines
Taking dextromethorphan polistirex with an amphetamine or an amphetamine-like medication can cause a group of symptoms called serotonin syndrome. These symptoms include:
 
  • Confusion
  • Hallucinations
  • A fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasms
  • Difficulty walking
  • Diarrhea.
 
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be dangerous.
 
CYP 2D6 Inhibitors
Dextromethorphan polistirex is broken down (metabolized) by certain enzymes in the liver, known as CYP 2D6 enzymes. Various other medications, known as CYP 2D6 inhibitors, slow down these enzymes, potentially leading to high levels of dextromethorphan polistirex in the bloodstream and perhaps increasing the risk of side effects. Check with your healthcare provider before combining such medications.
 
Ergot Medications
Combining dextromethorphan polistirex with an ergot medication can cause a group of symptoms called serotonin syndrome. These symptoms include:
 
  • Confusion
  • Hallucinations
  • A fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasms
  • Difficulty walking
  • Diarrhea.
 
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be dangerous.
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Dextromethorphan Polistirex Drug Information

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