Adcirca Drug Interactions

Adcirca Drug Interactions Explained

The following sections explain in detail the potential problems that can occur when Adcirca is combined with any of the drugs mentioned above.
 
Alpha Blockers
Taking Adcirca in combination with an alpha blocker may lead to low blood pressure (hypotension). If your blood pressure drops too low, you may experience symptoms such as dizziness, lightheadedness, or fainting. Do not use these medications together without your healthcare provider's approval. If you do combine them, your healthcare provider will need to monitor your blood pressure and may need to decrease your alpha blocker dosage.
 
Blood Pressure Medications
Taking Adcirca in combination with a high blood pressure medication may cause your blood pressure to decrease too much. Your healthcare provider may monitor your blood pressure more closely if you take Adcirca with a blood pressure medicine.
 
CYP 3A4 Inducer Medications
The body breaks down Adcirca using enzymes in the liver known as CYP 3A4 enzymes. Some other medications (known as CYP 3A4 inducers) can increase the activity of these enzymes. Combining Adcirca with one of these CYP 3A4 inducers may decrease the level of Adcirca in your body, making it less effective. Your healthcare provider may need to increase your Adcirca dose if you take it with a CYP 3A4 inducer.
 
CYP 3A4 Inhibitor Medications
The body breaks down Adcirca using enzymes in the liver known as CYP 3A4 enzymes. Some of other medications (known as CYP 3A4 inhibitors) can decrease the activity of these enzymes. Combining Adcirca with one of these CYP 3A4 inhibitors may increase the level of Adcirca in your body, increasing your risk for more side effects. Your healthcare provider may need to decrease your Adcirca dose if you take it with a CYP 3A4 inhibitor.

Adcirca Medication Information

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